Guadalupe on Main is a gluten-friendly Mexican restaurant and craft cocktail bar located on Main Street in Mesa. The restaurant specializes in flavors from Jalisco and operates as a craft kitchen with cocktails. Recently recognized by Phoenix Magazine as Best New Restaurant and Best Mexican Restaurant in their 2025 Best of the Valley awards. The establishment features a Chef's Test Kitchen and offers both dining and bar experiences.
Happy Hour
Specials
1/2 Bottles of Wine $1 Off Tacos Dorados $2 Off Drafts $3 Off Appetizers $4 Off Glasses of Wine $5 Select Cocktails
Amenities
Happy hours near Mesa
Phantom Fox Beer Co - Mesa
Phantom Fox Beer Company in Downtown Mesa is a community-driven brewery pouring 22 rotating craft beers on tap. The space blends a laid-back vibe with creative flavors, making it a welcoming stop for both casual sippers and craft beer enthusiasts. Guests can pair their drinks with nearby Goat and Ram Pizza, creating a perfect combination of local brews and bites. With daily happy hour specials and a friendly atmosphere, Phantom Fox is a standout in Mesa’s growing beer scene.
Gabby's Sports Bar and Grill
This neighborhood sports bar and grill in Mesa serves up what they call the valley's longest and most affordable happy hour running daily from 10 AM to 7 PM. The venue features classic bar fare including jumbo chicken wings, half-pound burgers with fries, and a full selection of drinks from domestic beers to well cocktails and wine. Gabby's offers entertainment throughout the week with karaoke nights, DJ music, and free pool on select days. The casual, family-friendly atmosphere centers around sports viewing with amenities like pool tables and regular weekly specials including all-you-can-eat wing night on Tuesdays.
The Hub Grill & Bar - Sossaman
The Hub Grill & Bar is a casual neighborhood restaurant and bar serving American comfort food with Southwest influences. The multi-location establishment features an extensive tap selection with domestic and craft beers, full bar service, and a menu that includes burgers, pizza, appetizers, and fish and chips. The venue offers gluten-free options and maintains a family-friendly atmosphere with kids eat free nights. Known for its consistent daily specials and happy hour programming, The Hub provides a relaxed setting for both dining and drinks.
Uncle Bear's Grill & Tap - Mesa Baseline
Uncle Bear's Grill & Tap is a casual dining establishment and bar featuring craft beer and grill fare in Mesa. The restaurant offers a family-friendly atmosphere with a full menu that includes hot dogs, lunch items, and various grilled options. With multiple locations across the Phoenix metro area, Uncle Bear's focuses on craft beer selections alongside their kitchen offerings. The venue provides both dine-in service and takeout options for guests.
The Hub Grill & Bar - Power
The Hub Grill & Bar is a casual neighborhood restaurant and bar serving American comfort food with Southwest influences. The multi-location establishment features an extensive tap selection with domestic and craft beers, full bar service, and a menu that includes burgers, pizza, appetizers, and fish and chips. The venue offers gluten-free options and maintains a family-friendly atmosphere with kids eat free nights. Known for its consistent daily specials and happy hour programming, The Hub provides a relaxed setting for both dining and drinks.
Uncle Bear's Grill & Tap - Mesa Greenfield
Uncle Bear's Grill & Tap is a casual dining establishment and bar featuring craft beer and grill fare in Mesa. The restaurant offers a family-friendly atmosphere with a full menu that includes hot dogs, lunch items, and various grilled options. With multiple locations across the Phoenix metro area, Uncle Bear's focuses on craft beer selections alongside their kitchen offerings. The venue provides both dine-in service and takeout options for guests.
Page Updated: 05/16/2026
*Prices and specials are subject to change at any time